Depression

Childhood maltreatment moderates the influence of genetic load for obesity on reward related brain structure and function in major depression

Obesity is a clinically relevant and highly prevalent somatic comorbidity of major depression (MDD). Genetic predisposition and history of childhood trauma have both independently been demonstrated to act as risk factors for obesity and to be …

Influence of electroconvulsive therapy on white matter structure in a diffusion tensor imaging study

BackgroundElectroconvulsive therapy (ECT) is a fast-acting intervention for major depressive disorder. Previous studies indicated neurotrophic effects following ECT that might contribute to changes in white matter brain structure. We investigated the …